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Study identifier: NCT04001829 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

Condition: Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage IA Breast Cancer AJCC v8 · Anatomic Stage IB Breast Cancer AJCC v8  ·  Sponsor: ECOG-ACRIN Cancer Research Group

PhasePhase 2
Planned participants249
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This phase II trial studies whether a prior germline predictor of taxane-induced peripheral neuropathy (TIPN) can help identify a subgroup of patients who are at higher risk of chemotherapy-induced peripheral neuropathy in African American patients with stages I-III breast cancer. The study also investigates whether docetaxel maybe work better than paclitaxel with regard to TIPN rate/severity and dose reductions.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (485)

University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United States
Anchorage Associates in Radiation MedicineAnchorage, Alaska, United States
Anchorage Radiation Therapy CenterAnchorage, Alaska, United States
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United States
Alaska Oncology and Hematology LLCAnchorage, Alaska, United States
Alaska Women's Cancer CareAnchorage, Alaska, United States
Anchorage Oncology CentreAnchorage, Alaska, United States
Katmai Oncology GroupAnchorage, Alaska, United States
Providence Alaska Medical CenterAnchorage, Alaska, United States
Fairbanks Memorial HospitalFairbanks, Alaska, United States
Kingman Regional Medical CenterKingman, Arizona, United States
Mercy Hospital Fort SmithFort Smith, Arkansas, United States

+ 473 more locations — full list on the registry record.

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