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Study identifier: NCT03872401 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Condition: Coronary Heart Disease (CHD)  ·  Sponsor: Amgen

PhasePhase 3
Planned participants12301
Who can joinAll sexes, 50 Years to 79 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (852)

North Alabama Research Center LLCAthens, Alabama, United States
Cardiovascular AssociatesBirmingham, Alabama, United States
Heart Center Research LLCHuntsville, Alabama, United States
Mobile Heart Specialists PCMobile, Alabama, United States
Arkansas CardiologyLittle Rock, Arkansas, United States
Central Arkansas Veterans Healthcare SystemLittle Rock, Arkansas, United States
Cardiovascular Research Foundation of Southern CaliforniaBeverly Hills, California, United States
Westside Medical Associates of Los AngelesBeverly Hills, California, United States
West Coast Research LLCDublin, California, United States
Desert Oasis Healthcare Medical GroupPalm Springs, California, United States
Covigilant Research, LLCRiverside, California, United States
Sierra Clinical ResearchRoseville, California, United States

+ 840 more locations — full list on the registry record.

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