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Study identifier: NCT03710291 Synced from ClinicalTrials.gov · August 09, 2026
● Study status: TerminatedVALOR-CKD

Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis

Condition: Metabolic Acidosis · Chronic Kidney Disease  ·  Sponsor: Tricida, Inc.

PhasePhase 3
Planned participants1480
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where203 locations · 34 countries
For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.Open the site landscape →

About this study

The purpose of this study is to evaluate the effect of TRC101 on the progression of chronic kidney disease (CKD) and to evaluate the safety profile of TRC101 in CKD patients with metabolic acidosis.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Estimated glomerular filtration rate (eGFR) 20 - 40 mL/min/1.73m\^2. * Serum bicarbonate 12 - 20 mEq/L. * On maximum tolerated dose of ACE inhibitor and/or ARB. Exclusion Criteria: * Acute metabolic acidosis. * Anticipated dialysis or kidney transplant within 6 months. * Recent acute kidney injury.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (203)

Investigative Site 4136Azusa, California, United States
Investigative Site 4148Denver, Colorado, United States
Investigative Site 4157Boca Raton, Florida, United States
Investigative Site 4146Bradenton, Florida, United States
Investigative Site 4102Coral Springs, Florida, United States
Investigative Site 4153Fort Lauderdale, Florida, United States
Investigative Site 4122Hollywood, Florida, United States
Investigative Site 4123Hollywood, Florida, United States
Investigative Site 4104Miami, Florida, United States
Investigative Site 4130Miami Lakes, Florida, United States
Investigative Site 4116Port Charlotte, Florida, United States
Investigative Site 4152Tampa, Florida, United States

+ 191 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

AzusaDenverBoca RatonBradenton

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