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Study identifier: NCT03431142 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Completed

Optimal antiPlatelet Therapy for High Bleeding and Ischemic RISK Patients Trial

Condition: Prolonged DAPT in ACS Patients With Hisk of Both Ischemic and Hemorrhage  ·  Sponsor: Shenyang Northern Hospital

PhasePhase 4
Planned participants7758
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

Current guidelines recommend that patients with ACS undergoing stent implantation might be offered extended DAPT treatment for up to 30 months if necessary. Therefore, we designed a prospective, multicenter, randomized, placebo-controlled trial among ACS patients with high-risk on ischemic and bleeding who received a new generation of DES and received 9 to 12 months of DAPT, and evaluated whether clopidogrel monotherapy reduce the risk of bleeding compared with clopidogrel plus ASA in the following 9 months and achieved non-inferior outcomes in preventing ischemic risk.

This description comes directly from the study's public registry record.

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Locations (103)

Anhui Provincial HospitalHefei, Anhui, China
The Seventh Medical Center of Pla General HospitalBeijing, Beijing Municipality, China
Beijing Anzhen Hospital,Capital Medical University, word2Beijing, Beijing Municipality, China
Beijing Anzhen Hospital,Capital Medical University, word3Beijing, Beijing Municipality, China
PLA Rocket Force Characteristic Medical CenterBeijing, Beijing Municipality, China
Peking University International HospitalBeijing, Beijing Municipality, China
Beijing Tsinghua Changgung HospitalBeijing, Beijing Municipality, China
Xinqiao Hospital Army Medical UniversityChongqing, Chongqing Municipality, China
Department of Cardiology, Daping Hospital, The Third Military Medical UniversityChongqing, Chongqing Municipality, China
University-Town Hospital Of Chongqing Medical UniversityChongqing, Chongqing Municipality, China
Fujian Medical University Union HospitalFuzhou, Fujian, China
Fujian Provincial HospitalFuzhou, Fujian, China

+ 91 more locations — full list on the registry record.

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