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Study identifier: NCT03419234 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Active Not Recruiting

Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

Condition: Castration Levels of Testosterone · Castration-Resistant Prostate Carcinoma · Metastatic Prostate Carcinoma in the Soft Tissue  ·  Sponsor: ECOG-ACRIN Cancer Research Group

PhasePhase 2
Planned participants223
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone therapy using abiraterone acetate and antiandrogen therapy may fight prostate cancer by lowering and/or blocking the use of androgens by the tumor cells. Drugs used in chemotherapy, such as cabazitaxel and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving abiraterone acetate and antiandrogen therapy with or without cabazitaxel and prednisone may help kill more tumor cells.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (672)

Fairbanks Memorial HospitalFairbanks, Alaska, United States
CTCA at Western Regional Medical CenterGoodyear, Arizona, United States
Kingman Regional Medical CenterKingman, Arizona, United States
Mercy Hospital Fort SmithFort Smith, Arkansas, United States
CHI Saint Vincent Cancer Center Hot SpringsHot Springs, Arkansas, United States
Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, Arkansas, United States
John L McClellan Memorial Veterans HospitalLittle Rock, Arkansas, United States
Kaiser Permanente-Deer Valley Medical CenterAntioch, California, United States
PCR OncologyArroyo Grande, California, United States
Sutter Auburn Faith HospitalAuburn, California, United States
Sutter Cancer Centers Radiation Oncology Services-AuburnAuburn, California, United States
Alta Bates Summit Medical Center-Herrick CampusBerkeley, California, United States

+ 660 more locations — full list on the registry record.

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