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Study identifier: NCT03414658 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

The AVIATOR Study: Trastuzumab and Vinorelbine With Avelumab OR Avelumab & Utomilumab in Advanced HER2+ Breast Cancer

Condition: Breast Cancer  ·  Sponsor: Adrienne G. Waks

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This research study is studying a combination of drugs as a possible treatment for breast cancer. The drugs involved in this study are: * Group A: Trastuzumab (Herceptin) + Vinorelbine (Navelbine) * Group B: Trastuzumab + Vinorelbine + Avelumab * Group C: Trastuzumab + Vinorelbine + Avelumab + Utomilumab (PF-05082566)

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (17)

University of Alabama at BirminghamBirmingham, Alabama, United States
University of California San FranciscoSan Francisco, California, United States
Georgetown University Medical CenterWashington D.C., District of Columbia, United States
University of Chicago Medical CenterChicago, Illinois, United States
Indiana University Health Melvin and Bren Simon Cancer CenterIndianapolis, Indiana, United States
Johns Hopkins UniversityBaltimore, Maryland, United States
Beth Israel Deaconess Medical CenterBoston, Massachusetts, United States
Dana-Farber Cancer InstituteBoston, Massachusetts, United States
Memorial Sloan-Kettering Cancer CenterNew York, New York, United States
Montefiore Medical CenterThe Bronx, New York, United States
University of Carolina at Chapel HillChapel Hill, North Carolina, United States
Duke University Medical CenterDurham, North Carolina, United States

+ 5 more locations — full list on the registry record.

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