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Study identifier: NCT03306680 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

SUNSET: SBRT for Ultra-central NSCLC- a Safety and Efficacy Trial

Condition: Non Small Cell Lung Cancer  ·  Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

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About this study

This multi-centre phase I dose-escalation study will use a time-to-event continual reassessment method (TIT-CRM). Accrual will start at level 1 (60 Gy in 8 fractions). Patients will be assigned to treatment doses using the TITE-CRM model. The model will use all available information from previously accrued patients to assign the highest dose with a predicted risk of grade 3 toxicity of 30% or less.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (7)

BC Cancer -Vancouver IslandVancouver, British Columbia, Canada
London Regional Cancer ProgramLondon, Ontario, Canada
Sunnybrook Odette Cancer CentreToronto, Ontario, Canada
Princess Margaret Cancer CentreToronto, Ontario, Canada
Centre Hospitalier de l'Universite de Montreal (CHUM)Montreal, Quebec, Canada
McGill University Health Centre-Cedars Cancer CentreMontreal, Quebec, Canada
Saskatoon Cancer CentreSaskatoon, Saskatchewan, Canada

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