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Study identifier: NCT03301220 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma

Condition: Smoldering Multiple Myeloma  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants390
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The primary objective of this study is to determine whether treatment with daratumumab administered subcutaneously (SC) prolongs progression-free survival (PFS) compared with active monitoring in participants with high-risk smoldering multiple myeloma (SMM).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (163)

Arizona Oncology Associates, PC - HALPhoenix, Arizona, United States
Innovative Clinical Research IncWhittier, California, United States
Miami Cancer InstituteMiami, Florida, United States
Emory UniversityAtlanta, Georgia, United States
University of Iowa Hospitals and ClinicsIowa City, Iowa, United States
East Jefferson General HospitalMetairie, Louisiana, United States
Dana Farber Cancer InstituteBoston, Massachusetts, United States
University of Michigan Comprehensive Cancer CenterAnn Arbor, Michigan, United States
Mayo ClinicRochester, Minnesota, United States
Washington UniversitySt Louis, Missouri, United States
VA Southern Nevada HealthcareNorth Las Vegas, Nevada, United States
New York Oncology HematologyAlbany, New York, United States

+ 151 more locations — full list on the registry record.

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