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Study identifier: NCT03197688 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States

Condition: Pulmonary Arterial Hypertension  ·  Sponsor: Actelion

PhaseN/A
Planned participants2200
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The Opsumit Users registry (OPUS; NCT02126943) was developed to characterize the safety profile of Opsumit and to describe clinical characteristics and outcomes of patients newly treated with Opsumit in the post-marketing setting. It is expected that the recruitment target of the OPUS registry cannot be achieved within the planned time period (5000 Opsumit new users by October 2018). The OrPHeUS study is designed to supplement the OPUS registry with retrospectively identified first-time Opsumit users in order to achieve the desired sample size.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (106)

Pulmonary AssociatesPhoenix, Arizona, United States
Cardiovascular ConsultantsPhoenix, Arizona, United States
Mayo Clinic - ArizonaPhoenix, Arizona, United States
University of California San DiegoLa Jolla, California, United States
Loma Linda University Medical CenterLoma Linda, California, United States
University of Southern CaliforniaLos Angeles, California, United States
David Geffen School of Medicine at University of California Los AngelesLos Angeles, California, United States
UCSF School of MedicineSan Francisco, California, United States
Paloma Medical GroupSan Juan Capistrano, California, United States
Santa Barbara Cottage HospitalSanta Barbara, California, United States
University of ColoradoAurora, Colorado, United States
National Jewish HealthDenver, Colorado, United States

+ 94 more locations — full list on the registry record.

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