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Study identifier: NCT02788474 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Completed

Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity Impairment

Condition: Idiopathic Pulmonary Fibrosis  ·  Sponsor: Boehringer Ingelheim

PhasePhase 4
Planned participants347
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

Identifying biomarkers to predict the clinical course and benefits of therapy early in the course of the disease remains one of the most urgent and relevant challenges to improve overall patient management, to prevent treatment delay or overtreatment. This study is conducted to examine the effect of nintedanib treatment on change in biomarkers indicative of extracellular matrix turnover which have been shown recently to correlate with disease progression. This study further aims to confirm the association of biomarker course during the first three months of treatment and disease progression.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (86)

Jasper Summit Research, LLCJasper, Alabama, United States
Western Connecticut Medical GroupDanbury, Connecticut, United States
St. Francis Medical InstituteClearwater, Florida, United States
University of Florida College of MedicineJacksonville, Florida, United States
Minnesota Lung CenterMinneapolis, Minnesota, United States
The Lung Research Center, LLCChesterfield, Missouri, United States
Clinical Research SolutionsDayton, Ohio, United States
Pulmonary Associates of Richmond, Inc.Richmond, Virginia, United States
Royal Prince Alfred HospitalCamperdown, Sydney, New South Wales, Australia
Concord General Repatriation Hospital -Ambulatory Care UnitConcord, New South Wales, Australia
Royal Adelaide HospitalAdelaide, South Australia, Australia
The Alfred HospitalMelbourne, Victoria, Australia

+ 74 more locations — full list on the registry record.

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