EICHORCondition: Anatomic Stage III Breast Cancer AJCC v8 · Anatomic Stage IV Breast Cancer AJCC v8 · Breast Adenocarcinoma · Sponsor: National Cancer Institute (NCI)
This randomized phase III trial studies exemestane and entinostat to see how well they work compared to exemestane alone in treating patients with hormone receptor-positive breast cancer that has spread to nearby tissue or lymph nodes (locally advanced) or another place in the body (metastatic). Estrogen can cause the growth of breast cancer cells. Endocrine therapy using exemestane may fight breast cancer by lowering the amount of estrogen the body makes. Entinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether exemestane is more effective with or without entinostat in treating breast cancer.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | — |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro, Arkansas, United States | — |
| Mercy San Juan Medical Center | Carmichael, California, United States | — |
| Enloe Medical Center | Chico, California, United States | — |
| Adventist Health Cancer Care Center Chico | Chico, California, United States | — |
| Community Cancer Institute | Clovis, California, United States | — |
| University Oncology Associates | Clovis, California, United States | — |
| Eisenhower Medical Center | Rancho Mirage, California, United States | — |
| Mercy Cancer Center - Sacramento | Sacramento, California, United States | — |
| Saint Helena Hospital | St. Helena, California, United States | — |
| Presbyterian Intercommunity Hospital | Whittier, California, United States | — |
| Woodland Memorial Hospital | Woodland, California, United States | — |
+ 641 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT02115282