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Study identifier: NCT02006485 Synced from ClinicalTrials.gov · August 09, 2026
● Study status: Completed

Ublituximab in Combination With TGR-1202 +/- Ibrutinib or Bendamustine in Patients With B-cell Malignancies

Condition: Chronic Lymphocytic Leukemia · Non-Hodgkin's Lymphoma  ·  Sponsor: TG Therapeutics, Inc.

PhasePhase 1
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where6 locations
For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

The purpose of this study is to evaluate the safety and effectiveness of Ublituximab in combination with TGR-1202, with or without ibrutinib or bendamustine, in patients with advanced hematologic malignancies

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Confirmed B-cell non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and other B-cell lymphoproliferative disorders as approved by the Medical Monitor or Study Chair * Refractory to or relapsed after at least 1 prior treatment regimen * Eastern Cooperative Oncology Group (ECOG) score of 0 to 2 Exclusion Criteria: * Any major surgery, chemotherapy or immunotherapy within the last 21 days * Known hepatitis B virus, hepatitis C virus or HIV infection * Autologous hematologic stem cell transplant within 3 months of study entry or Allogeneic hematologic stem cell transplant within 12 months * Primary central nervous system lymphoma or known intracranial involvement

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (6)

TG Therapeutics Investigational Trial SiteHuntsville, Alabama, United States
TG Therapeutics Investigational Trial SiteJonesboro, Arkansas, United States
TG Therapeutics Investigational Trial SiteDuarte, California, United States
TG Therapeutics Investigational Trial SiteAtlanta, Georgia, United States
TG Therapeutics Investigational Trial SiteOmaha, Nebraska, United States
MD Anderson Cancer CenterHouston, Texas, United States

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

HuntsvilleJonesboroDuarteAtlanta

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