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Study identifier: NCT01760005 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Condition: Alzheimers Disease · Dementia · Alzheimers Disease, Familial  ·  Sponsor: Washington University School of Medicine

PhasePhase 2/Phase 3
Planned participants490
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The purpose of this study is to assess the safety, tolerability, biomarker, cognitive and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug slows the rate of progression of cognitive/clinical impairment or improves disease-related biomarkers.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (38)

University of Alabama in BirminghamBirmingham, Alabama, United States
University of California San Diego Medical CenterLa Jolla, California, United States
USC Keck School of MedicineLos Angeles, California, United States
Yale University School of MedicineNew Haven, Connecticut, United States
Emory UniversityAtlanta, Georgia, United States
Advocate Lutheran General HospitalPark Ridge, Illinois, United States
Indiana University School of MedicineIndianapolis, Indiana, United States
Washington University in St. LouisSt Louis, Missouri, United States
University of PittsburghPittsburgh, Pennsylvania, United States
Butler HospitalProvidence, Rhode Island, United States
Kerwin Medical CenterDallas, Texas, United States
University of WashingtonSeattle, Washington, United States

+ 26 more locations — full list on the registry record.

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