EICHORCondition: Advanced Adult Hepatocellular Carcinoma · Recurrent Hepatocellular Carcinoma · Stage III Hepatocellular Carcinoma AJCC v7 · Sponsor: National Cancer Institute (NCI)
This randomized phase III trial studies sorafenib tosylate and doxorubicin hydrochloride to see how well they work compared with sorafenib tosylate alone in treating patients with liver cancer that has spread to nearby tissue or lymph nodes or has spread to other places in the body. Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as doxorubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving sorafenib tosylate together with doxorubicin hydrochloride is more effective than sorafenib tosylate alone in treating liver cancer.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
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| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | — |
| Providence Hospital | Mobile, Alabama, United States | — |
| Southern Cancer Center PC-Providence | Mobile, Alabama, United States | — |
| Alaska Regional Hospital | Anchorage, Alaska, United States | — |
| Fairbanks Memorial Hospital | Fairbanks, Alaska, United States | — |
| Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro, Arkansas, United States | — |
| Kaiser Permanente-Anaheim | Anaheim, California, United States | — |
| Kaiser Permanente-Deer Valley Medical Center | Antioch, California, United States | — |
| PCR Oncology | Arroyo Grande, California, United States | — |
| Kaiser Permanente-Baldwin Park | Baldwin Park, California, United States | — |
| Kaiser Permanente-Bellflower | Bellflower, California, United States | — |
| East Bay Radiation Oncology Center | Castro Valley, California, United States | — |
+ 661 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT01015833