EICHORCondition: Recurrent Uterine Corpus Sarcoma · Stage IIIA Uterine Sarcoma · Stage IIIB Uterine Sarcoma · Sponsor: National Cancer Institute (NCI)
This randomized phase III trial is studying gemcitabine hydrochloride, docetaxel, and bevacizumab to see how well they work compared with gemcitabine hydrochloride, docetaxel, and a placebo in treating patients with advanced or recurrent uterine leiomyosarcoma. Drugs used in chemotherapy, such as gemcitabine hydrochloride and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. It is not yet known whether gemcitabine hydrochloride and docetaxel are more effective when given with or without bevacizumab in treating uterine leiomyosarcoma.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
| Saint Joseph's Hospital and Medical Center | Phoenix, Arizona, United States | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank, California, United States | — |
| John Muir Medical Center-Concord Campus | Concord, California, United States | — |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles, California, United States | — |
| Los Angeles County-USC Medical Center | Los Angeles, California, United States | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles, California, United States | — |
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles, California, United States | — |
| Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View, California, United States | — |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange, California, United States | — |
| University of California San Diego | San Diego, California, United States | — |
| UCSF Medical Center-Mount Zion | San Francisco, California, United States | — |
+ 189 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT01012297