EICHORCondition: Cancer Of Prostate · Prostate Cancer · Prostatic Neoplasms · Sponsor: National Cancer Institute (NCI)
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Background: * It is not fully understood why prostate cancer in some men becomes androgen-independent (no longer responds to anti-androgen medication), but genetics likely plays an important role. * Genes contain the hereditary information that is passed down from parents to children. Although everyone has the same set of genes, individuals can have different forms of the same gene. * Differences in genes may explain, at least in part, why some people develop a more aggressive form of prostate cancer than others. Objectives: -To obtain blood samples from patients with prostate cancer to try to identify gene differences associated with progression to the androgen independent state. Eligibility: -All participants participating in NCI prostate cancer protocols. Design: * Participants with prostate cancer are evaluated in the NCI s Medical Oncology Clinic. * Blood samples are collected at the initial visit or at follow-up visits. * DNA (genetic material) and white blood cells are extracted from these samples to be used for genotyping and establishment of cell lines. * Gene variations are correlated with prostate cancer prognosis and prognostic indicators.
This description comes directly from the study's public registry record.
Paula A Carter, R.N. · (240) 858-3191 · pcartera@mail.nih.gov
William D Figg, Pharm.D. · (240) 760-6179 · figgw@mail.nih.gov
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
* INCLUSION CRITERIA: Individuals 18 years of age and older are eligible. Individuals with a diagnosis of prostate cancer are eligible. EXCLUSION CRITERIA: Children are not eligible.
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| National Institutes of Health Clinical Center | Bethesda, Maryland, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT00923221