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Study identifier: NCT00922272 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Completed

Efficacy, Safety, and Tolerability of SPD489 in Adults With Schizophrenia and Predominant Negative Symptoms

Condition: Schizophrenia and Predominant Negative Symptoms  ·  Sponsor: Shire

PhasePhase 2
Planned participants92
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where27 locations

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

To explore the efficacy of SPD489, as adjunctive therapy to a stable dose of atypical antipsychotic medication, on negative symptoms in adult subjects with clinically stable schizophrenia and predominant negative symptoms, as measured by the Scale for the Assessment of Negative Symptoms (SANS).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Adults aged 18-55 * Clinically stable Schizophrenia and predominant negative symptoms * Taking a stable dose of antipsychotic medication Exclusion Criteria: * Clinically notable positive symptoms defined by PANSS

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (27)

K&S Professional Research ServicesLittle Rock, Arkansas, United States
South Coast Clinical TrialsAnaheim, California, United States
Omega Clinical TrialsAnaheim, California, United States
Clinical InnovationsCosta Mesa, California, United States
Collaborative Neuroscience Network, Inc.Garden Grove, California, United States
Apostle Clinical Trials, Inc.Long Beach, California, United States
Excell Research, Inc.Oceanside, California, United States
Southcoast Clinical TrialsSan Bernardino, California, United States
CNRI San Diego & Los AngelesSan Diego, California, United States
Affiliated Research InstituteSan Diego, California, United States
Artemis Institute for Clinical ResearchSan Diego, California, United States
Neuropsychiatric Research Center of Orange CountySanta Ana, California, United States

+ 15 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

Little RockAnaheimCosta MesaGarden Grove

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