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Study identifier: NCT00678392 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Completed

Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell Cancer

Condition: Kidney Neoplasms  ·  Sponsor: Pfizer

PhasePhase 3
Planned participants723
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where294 locations · 22 countries

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The study is designed to demonstrate that axitinib (AG-013736) is superior to sorafenib in delaying tumor progression in patients with metastatic renal cell cancer after failure of one first line regimen.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Histologically or cytologically confirmed renal cell cancer with a component of clear cell subtype, with metastasis * Evidence of measurable disease * Must have failed one prior systemic first-line regimen for metastatic renal cell cancer Exclusion Criteria: * Prior treatment for metastatic renal cell cancer with more that one systemic first line therapy * Major surgery less than 4 weeks or radiation less than 2 weeks of starting study drug

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (294)

East Valley Hematology and Oncology Medical GroupBurbank, California, United States
Maurice Berkowtiz, MDBurbank, California, United States
Agajanian Institute of Oncology and HematologyDowney, California, United States
Los Angeles Hematology/Oncology Medical GroupGlendale, California, United States
Los Angeles Hematology/Oncology Medical GroupLos Angeles, California, United States
LAC-USC Medical CenterLos Angeles, California, United States
USC Norris Cancer Hospital and ClinicsLos Angeles, California, United States
Kenmar Research InstituteLos Angeles, California, United States
Metropolitan Hematology/Oncology Medical GroupLos Angeles, California, United States
Ronald Regan UCLA Medical CenterLos Angeles, California, United States
UCLALos Angeles, California, United States
Agajanian Institute of Oncology and HematologyMontebello, California, United States

+ 282 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

BurbankDowneyGlendaleLos Angeles

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