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Study identifier: NCT00567580 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Unknown

Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer

Condition: Prostate Cancer  ·  Sponsor: Radiation Therapy Oncology Group

PhasePhase 3
Planned participants1792
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as flutamide, bicalutamide, and luteinizing hormone-releasing hormone agonist, may lessen the amount of androgens made by the body. It is not yet known which regimen of radiation therapy with or without androgen-deprivation therapy is more effective for prostate cancer. PURPOSE: This randomized phase III trial is studying prostate radiation therapy to see how well it works compared with short-term androgen deprivation therapy given together with pelvic lymph node radiation therapy with or without prostate radiation therapy in treating patients with a rising PSA after surgery for prostate cancer.

This description comes directly from the study's public registry record.

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Locations (460)

UAB Comprehensive Cancer CenterBirmingham, Alabama, United States
Fairbanks Cancer Treatment Center at Fairbanks Memorial HospitalFairbanks, Alaska, United States
Arizona Center for Cancer Care - PeoriaPeoria, Arizona, United States
Arizona Oncology Services FoundationPhoenix, Arizona, United States
Arizona Oncology - TucsonTucson, Arizona, United States
Auburn Radiation OncologyAuburn, California, United States
Peninsula Medical CenterBurlingame, California, United States
Radiation Oncology Centers - Cameron ParkCameron Park, California, United States
Mercy Cancer Center at Mercy San Juan Medical CenterCarmichael, California, United States
East Bay Radiation Oncology CenterCastro Valley, California, United States
Valley Medical Oncology Consultants - Castro ValleyCastro Valley, California, United States
Enloe Cancer Center at Enloe Medical CenterChico, California, United States

+ 448 more locations — full list on the registry record.

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