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Study identifier: NCT00379340 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumor

Condition: Stage III Kidney Wilms Tumor · Stage IV Kidney Wilms Tumor  ·  Sponsor: Children's Oncology Group

PhasePhase 3
Planned participants395
Who can joinAll sexes, N/A to 29 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This phase III trial is studying how well combination chemotherapy with or without radiation therapy works in treating young patients with newly diagnosed stage III or stage IV Wilms' tumor. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving more than one drug (combination chemotherapy) with or without radiation therapy may kill more tumor cells.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (227)

Children's Hospital of AlabamaBirmingham, Alabama, United States
University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United States
USA Health Strada Patient Care CenterMobile, Alabama, United States
Phoenix Childrens HospitalPhoenix, Arizona, United States
Banner University Medical Center - TucsonTucson, Arizona, United States
Arkansas Children's HospitalLittle Rock, Arkansas, United States
University of Arkansas for Medical SciencesLittle Rock, Arkansas, United States
Kaiser Permanente Downey Medical CenterDowney, California, United States
Loma Linda University Medical CenterLoma Linda, California, United States
Miller Children's and Women's Hospital Long BeachLong Beach, California, United States
Children's Hospital Los AngelesLos Angeles, California, United States
Cedars-Sinai Medical CenterLos Angeles, California, United States

+ 215 more locations — full list on the registry record.

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