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Condition: Unresectable Soft Tissue Sarcoma Synced from ClinicalTrials.gov · July 29, 2026

Recruiting studies: Unresectable Soft Tissue Sarcoma

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcom
Phase 1/Phase 2 · 6 location(s) · GlaxoSmithKline · NCT07602777Tumor Neoantigen Vaccine SarVac Combined With Tumor Specific Lymphocyte Reinfusion in the Treatment of Advanced Sarcoma
Phase 1 · 1 location(s) · Sun Yat-sen University · NCT07648069First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma
Phase 1/Phase 2 · 8 location(s) · Adcendo ApS · NCT06797999Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-
Phase N/A · 8 location(s) · Novartis Pharmaceuticals · NCT05868629IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)
Phase 2 · 1 location(s) · Fudan University · NCT06849986Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Diffe
Phase 3 · 257 location(s) · National Cancer Institute (NCI) · NCT06422806Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Adv
Phase 1 · 16 location(s) · National Cancer Institute (NCI) · NCT05711615Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcom
Phase 2 · 2 location(s) · M.D. Anderson Cancer Center · NCT05019703A Study of Ivonescimab in People With Leiomyosarcoma
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT07516925Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
Phase 1/Phase 2 · 1 location(s) · Memorial Sloan Kettering Cancer Center · NCT04577014Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresecta
Phase 2 · 2 location(s) · Wake Forest University Health Sciences · NCT07291297ACTengine® IMA203 Combined With mRNA-4203
Phase 1 · 4 location(s) · Immatics US, Inc. · NCT06946225Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma
Phase 2 · 1 location(s) · Fujun Zhang · NCT05894018A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
Phase 1 · 6 location(s) · Angiex, Inc. · NCT06440005Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial
Phase 2 · 13 location(s) · National Cancer Institute (NCI) · NCT05333458Clinical Trials of Benmelstobart Injection Combined With Anlotinib Hydrochloride Capsules in the Treatment of Advanced o
Phase 2 · 15 location(s) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · NCT07548177Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Phase 1/Phase 2 · 1 location(s) · Mayo Clinic · NCT05269381A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma
Phase 1/Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT06843967Adriamycin and Ifosfamide Combined With Sintilimab
Phase 2 · 1 location(s) · Sun Yat-sen University · NCT04589754XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Tran
Phase 2 · 1 location(s) · Northwestern University · NCT06571734Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Phase 1/Phase 2 · 1 location(s) · Roswell Park Cancer Institute · NCT03965234Cryoablation Plus Camrelizumab for Advanced Soft Tissue Sarcoma
Phase 2 · 1 location(s) · Sun Yat-sen University · NCT07602049A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
Phase 2 · 2 location(s) · Sarcoma Alliance for Research through Collaboration · NCT06942442Toripalimab Combined With CAV/IE Regimen
Phase 2 · 1 location(s) · Sun Yat-sen University · NCT04589741A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Parti
Phase 2 · 54 location(s) · Bayer · NCT06760819
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.