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Study identifier: NCT06440005 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Condition: Cancer · Advanced Cancer · Locally Advanced Carcinoma  ·  Sponsor: Angiex, Inc.

PhasePhase 1
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously. Dosing of AGX101 will be repeated once every 3, 6 or 9 weeks. Participants may continue study treatment until disease progression, unacceptable toxicity, or consent withdrawal. Subjects will attend an end of treatment visit and will receive two safety follow-up telephone contacts up to 90 days following the last dose of study drug.

This description comes directly from the study's public registry record.

Talk to the study team

Glen Weiss, MD  ·  857-203-7808  ·  trials@angiex.com

Always discuss trial participation with your own doctor first.

Locations (6)

USC/Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
Florida Cancer SpecialistSarasota, Florida, United StatesRecruiting
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
Sarah Cannon Research CenterNashville, Tennessee, United StatesRecruiting
NEXT OncologySan Antonio, Texas, United StatesRecruiting
NEXT OncologyFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06440005