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Study identifier: NCT07291297 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Condition: Sarcoma Metastatic · Sarcoma, Soft Tissue  ·  Sponsor: Wake Forest University Health Sciences

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is to see how metformin, when used in combination with standard of care (SOC) treatment for metastatic (cancer that has spread) soft tissue sarcoma can improve patient outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Leah Wilson, RN  ·  980-442-2333  ·  Leah.J.Wilson@advocatehealth.org

Megan Jagosky, MD  ·  704-446-1242  ·  Megan.Jagosky@advocatehealth.org

Always discuss trial participation with your own doctor first.

Locations (2)

Levine Cancer InstituteCharlotte, North Carolina, United StatesRecruiting
Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07291297