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Study identifier: NCT06843967 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma

Condition: Well Differentiated Liposarcoma · Dedifferentiated Liposarcoma · Liposarcoma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1/Phase 2
Planned participants54
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to find out whether mirdametinib in combination with palbociclib is an effective and safe treatment for people with metastatic, recurrent, and unresectable liposarcoma. This study will test different doses of mirdametinib in combination with a fixed dose of palbociclib to find the best safe dose for further testing.

This description comes directly from the study's public registry record.

Talk to the study team

Olayode Babatunde, MD  ·  646-888-4363  ·  zzPDL_MED_Sarcoma_Clinical_Trials@mskcc.org

William Tap, MD  ·  646-888-4163  ·  zzPDL_MED_Sarcoma_Clinical_Trials@mskcc.org

Always discuss trial participation with your own doctor first.

Locations (7)

Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Cancer Center Suffolk- Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06843967