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Condition: Severe Mitral Regurgitation Synced from ClinicalTrials.gov · July 29, 2026

Recruiting studies: Severe Mitral Regurgitation

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients
NA · 1 location(s) · Saint Petersburg State University, Russia · NCT06377449Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe
NA · 50 location(s) · HighLife SAS · NCT04029363Efficacy and Safety of Catheter abLation in patiEnts With seVere mitrAl regurgiTation and pErsistent Atrial Fibrillation
NA · 17 location(s) · Beijing Anzhen Hospital · NCT06883864Novel 3-dimensional Echocardiographic Quantification of Mitral Regurgitant Volume
Phase N/A · 1 location(s) · Germans Trias i Pujol Hospital · NCT07528781A Clinical Study of GeminiOne TEER System for the Treatment of Severe, Symptomatic MR.
NA · 1 location(s) · Sierra Valve LLC · NCT07086534The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study
NA · 5 location(s) · Half Moon Medical · NCT04343313The Prospective Segeberg Registry for Mitral Transcatheter Edge-to-Edge Repair
Phase N/A · 1 location(s) · Segeberger Kliniken GmbH · NCT07045753Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in P
NA · 8 location(s) · InnovHeart · NCT06414265Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation
NA · 2 location(s) · Centre Hospitalier Universitaire, Amiens · NCT03389542TEER for Severe DMR of Low to Intermediate Surgery Risk
Phase N/A · 1 location(s) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · NCT06162780Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or S
NA · 1 location(s) · Peijia Medical Technology (Suzhou) Co., Ltd. · NCT05610566Management and Clinical Outcomes of Patients With Severe Mitral Valve Disease Not Suitable for Surgery
Phase N/A · 3 location(s) · French Cardiology Society · NCT02925819Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation
Phase N/A · 6 location(s) · UMC Utrecht · NCT03975998Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or
NA · 1 location(s) · Peijia Medical Technology (Suzhou) Co., Ltd. · NCT05655897Mi-thos® Transcatheter Mitral Valve Replacement Study
NA · 3 location(s) · Shanghai NewMed Medical Co., Ltd. · NCT04195984Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Tra
NA · 1 location(s) · Insel Gruppe AG, University Hospital Bern · NCT04913727HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve
NA · 14 location(s) · HighLife SAS · NCT048882475-HTP and Creatine for Depression R33 Phase
Phase 2 · 1 location(s) · University of Utah · NCT05895747First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve
NA · 10 location(s) · Epygon · NCT04775108Annuloplasty for Not-Severe TR in Patients Undergoing MV Repair Versus Mitral Repair Only (NOSTRUM)
NA · 3 location(s) · Ospedale San Raffaele · NCT02996552Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitr
NA · 85 location(s) · Medtronic Cardiovascular · NCT03242642The Feasibility Study of Polymer Artificial Heart Valve for the Treatment the Mitral Valve Disease.
NA · 1 location(s) · Shanghai HeartEpoch Medical Technology Co., Ltd · NCT07243184The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).
NA · 17 location(s) · Mayra Guerrero · NCT04408430Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial
NA · 37 location(s) · Medtronic Cardiovascular · NCT05496998
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.