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Study identifier: NCT06414265 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in Patients With Severe Symptomatic Mitral Regurgitation

Condition: Heart Failure  ·  Sponsor: InnovHeart

PhaseNA
Planned participants30
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate feasibility, safety, and performance of the SATURN TS TMVR System for the treatment of moderate-to-severe or severe, symptomatic mitral regurgitation through a transcatheter approach. The main questions it aims to answer are: * is the use of the device feasible? * is it safe (defined as freedom from device-related major adverse events at 30 days)? * does it perform (defined as reduction of MR Grade to ≤ 1+ at 30 days)? Participants will need to do the following as part of the clinical trial: * complete 6-Minute Walking Test * complete Quality of Life Questionnaires * undergo blood evaluations * CT scan * 12 lead ECG * Transesophageal Echocardiography * Transthoracic Echocardiogram * the study procedure (valve implantation, right heart catheterization, left arterial pressure, fluoroscopy/ angiogram)

This description comes directly from the study's public registry record.

Talk to the study team

VP, Clinical Affairs InnovHeart  ·  +49 69 24003626  ·  a.roach@innovheart.com

Maxis Operations  ·  maxisoperations@maxismedical.com

Always discuss trial participation with your own doctor first.

Locations (8)

Tbilisi Heart and Vascular ClinicTbilisi, GeorgiaRecruiting
Tbilisi Heart CenterTbilisi, GeorgiaRecruiting
Ospedale San RaffaeleMilan, ItalyRecruiting
Instituto Clinico HumanitasMilan, ItalyRecruiting
Vilnius University Hospital Santaros KlinikosVilnius, LithuaniaRecruiting
Górnośląskie Centrum MedyczneKatowice, PolandRecruiting
Warsaw Medical UniversityWarsaw, PolandRecruiting
Royal Sussex County HospitalBrighton, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06414265