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Study identifier: NCT04775108 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

Condition: Mitral Valve Regurgitation  ·  Sponsor: Epygon

PhaseNA
Planned participants40
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

The EPYGON VALVE is an innovative mitral valve, intended for valve replacement of a native mitral valve through a minimally invasive implant procedure by means of a dedicated implant device. The EPYGON VALVE is a bio prosthesis, composed by a functional assembly of bovine pericardium on a NiTinol stent. The purpose of this trial is to assess the safety and feasibility of the Epygon™ Transcatheter mitral valve and the transapical delivery system, in adult patients with severe, symptomatic mitral regurgitation.

This description comes directly from the study's public registry record.

Talk to the study team

Christophe Giot  ·  +33 4 42 95 12 20  ·  christophe.giot@affluentmedical.com

Always discuss trial participation with your own doctor first.

Locations (10)

Medical University of InnsbruckInnsbruck, AustriaRecruiting
Medical University of Vienna - Department of Surgery, Division of Cardiac SurgeryVienna, AustriaRecruiting
Careggi Hospital Florence Italy Largo BrambillaFlorence, ItalyRecruiting
A.O.U. Citta della Salute e della Scienza di TorinoTorino, ItalyRecruiting
Dedinje Cardiovascular InstituteBelgrade, SerbiaNot Yet Recruiting
Hospital German Trias i PujolBadalona, SpainRecruiting
Hospital de la Santa Creu i Sant PauBarcelona, SpainRecruiting
Hospital Clinico San CarlosMadrid, SpainRecruiting
Hospital Virgen de la ArrixacaMurcia, SpainRecruiting
Hospital Universitario Virgen Del RocioSeville, SpainNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04775108