Condition: Mitral Annular Calcification · Mitral Stenosis · Mitral Regurgitation · Sponsor: Mayra Guerrero
A prospective multicenter study enrolling high surgical risk patients with severe mitral annular calcification (MAC) and symptomatic mitral valve dysfunction (severe stenosis, ≥ moderate to severe regurgitation, or mixed ≥ moderate stenosis and ≥ regurgitation). There are 2 Arms in this study: 1) "Transseptal (TS) Valve-in-MAC" (ViMAC) Arm, and 2) Natural History of Disease Registry (NHDR) for patients treated with medical treatment only (which includes patients who meet inclusion criteria but can't be treated with transeptal ViMAC due to the presence of anatomical exclusion criteria or other exclusion criteria) and have not had other procedures that may impact outcomes (i.e., alcohol septal ablation or radiofrequency ablation). The study also includes a Registry of Permanently Unassigned" for subjects who undergo preemptive septal ablation procedures (alcohol or radiofrequency) in anticipation of continuing onto ViMAC arm, but are not accepted in the ViMAC Study arm or the patient chooses not to undergo ViMAC procedure.
This description comes directly from the study's public registry record.
Tatiana Kaptzan, Ph. D. · 507-284-1610 · kaptzan.tatiana@mayo.edu
Always discuss trial participation with your own doctor first.
| Dignity Health Chandler Regional Medical Center | Gilbert, Arizona, United States | Recruiting |
| Banner - University Medicine Cardiology Clinic | Phoenix, Arizona, United States | Recruiting |
| Pima Heart & Vascular | Tucson, Arizona, United States | Recruiting |
| Cedars-Sinai Medical Center | Los Angeles, California, United States | Recruiting |
| Sutter Health | San Francisco, California, United States | Recruiting |
| Uchealth Heart & Vascular Clinic Harmony Campus | Fort Collins, Colorado, United States | Active Not Recruiting |
| Medstar Washington Hospital Center | Washington D.C., District of Columbia, United States | Recruiting |
| Massachusetts General Hospital | Boston, Massachusetts, United States | Recruiting |
| Brigham and Women's Hospital | Boston, Massachusetts, United States | Recruiting |
| Mayo Clinic | Rochester, Minnesota, United States | Active Not Recruiting |
| Columbia University Medical Center/NYPH | New York, New York, United States | Recruiting |
| Oklahoma Heart Institute Utica Office | Tulsa, Oklahoma, United States | Recruiting |
+ 5 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT04408430