Condition: Neurofibromatosis Type 1 Nf1 Synced from ClinicalTrials.gov · August 06, 2026

Recruiting studies: Neurofibromatosis Type 1 Nf1

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST
Phase 1/Phase 2 · 2 location(s) · AeRang Kim · NCT06735820
Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas
Phase 1/Phase 2 · 1 location(s) · National Cancer Institute (NCI) · NCT04750928
Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
Phase 2 · 15 location(s) · University of Alabama at Birmingham · NCT06188741
Natural History Study of Patients With Neurofibromatosis Type 2
Phase N/A · 1 location(s) · National Institute of Neurological Disorders and Stroke (NIN · NCT00598351
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillome
NA · 2 location(s) · National Cancer Institute (NCI) · NCT06507748
Prevalence, Clinical Characteristics, Progression, and Management of Neurofibromatosis Type 1 in Egypt (NF1-Egy)
Phase N/A · 9 location(s) · AstraZeneca · NCT07221331
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
Phase N/A · 3 location(s) · Universidad Nacional Autonoma de Mexico · NCT06523582
Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy
NA · 1 location(s) · Massachusetts General Hospital · NCT07233408
Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonan
NA · 1 location(s) · Nicole Baca · NCT04763109
GROWing Up With Rare GENEtic Syndromes
Phase N/A · 1 location(s) · dr. Laura C. G. de Graaff-Herder · NCT04463316
Evaluation of Percutaneous Cryotherapy in the Treatment of Plexiform Neurofibromas and Unresectable Neurofibromas in Neu
NA · 1 location(s) · Centre Leon Berard · NCT05199376
Neurofibromatosis (NF) Registry Portal
Phase N/A · 1 location(s) · The Children's Tumor Foundation · NCT01885767
Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis
Phase N/A · 1 location(s) · National Cancer Institute (NCI) · NCT06880991
Glioma Developmental and HyperActive Ras Tumor (DHART) Board
Phase N/A · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05489783
Clinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsia
Phase N/A · 16 location(s) · AstraZeneca · NCT07088991
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
Phase 3 · 132 location(s) · National Cancer Institute (NCI) · NCT04166409
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
Phase N/A · 1 location(s) · Assistance Publique - Hôpitaux de Paris · NCT06147414
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and
Phase N/A · 6 location(s) · National Cancer Institute (NCI) · NCT02544022
A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
Phase 2 · 14 location(s) · Healx Limited · NCT06541847
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
Phase 2 · 6 location(s) · Scott R. Plotkin, MD, PhD · NCT04374305
Mirdametinib in Patients With Advanced NF1-mutant Melanoma
Phase 2 · 1 location(s) · Kevin Kim, MD · NCT07237100
PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas
Phase 1 · 5 location(s) · Pasithea Therapeutics Corp. · NCT06961565
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and F
NA · 1 location(s) · National Cancer Institute (NCI) · NCT05361811
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractor
Phase 1 · 1 location(s) · National Cancer Institute (NCI) · NCT02390752
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy
Phase 2 · 25 location(s) · University Hospital, Strasbourg, France · NCT05180825
FARD (RaDiCo Cohort) (RaDiCo-FARD)
Phase N/A · 15 location(s) · Institut National de la Santé Et de la Recherche Médicale, F · NCT05954416
Real-World Treatment Study of Koselugo (Selumetinib)
Phase N/A · 12 location(s) · AstraZeneca · NCT06360406
Familial Investigations of Childhood Cancer Predisposition
Phase N/A · 1 location(s) · St. Jude Children's Research Hospital · NCT03050268
RASopathy Biorepository
Phase N/A · 1 location(s) · Children's Hospital Medical Center, Cincinnati · NCT04395495
Immunotherapy Based on Antigen-specific Immune Effector Cells Targeting Neurofibromatosis or Schwannomatosis
Phase 1/Phase 2 · 1 location(s) · Shenzhen Geno-Immune Medical Institute · NCT04085159
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