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Study identifier: NCT07237100 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Condition: Advanced Unresectable Melanoma · Metastatic Melanoma  ·  Sponsor: Kevin Kim, MD

PhasePhase 2
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate clinical efficacy of mirdametinib in patients with advanced NF1-mutant melanoma whose disease has progressed while on or after previous immunotherapy. The main questions this study aims to answer are: * To evaluate the feasibility of conducting a prospective single-center clinical trial of mirdametinib in patients with advanced NF1-mutant melanoma whose disease progresses during or after PD-1 antibody-based checkpoint inhibitor therapy. * To evaluate preliminary clinical efficacy of mirdametinib in patients with advanced NF1-mutant melanoma whose disease has progressed while on or after previous immunotherapy * To evaluate the safety profile of mirdametinib in patients with advanced NF1-mutant melanoma

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Research at Sutter Health  ·  415-600-1544  ·  clinicalresearch@sutterhealth.org

Andrea Davila  ·  andrea.davila@sutterhealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

California Pacific Medical Center - Sutter HealthSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07237100