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Condition: Moderate To Severe Ulcerative Colitis Synced from ClinicalTrials.gov · August 04, 2026

Recruiting studies: Moderate To Severe Ulcerative Colitis

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Phase 2 · 129 location(s) · Gilead Sciences · NCT06029972
A Study of Vedolizumab SC Given to Adults With Moderate to Severe Ulcerative Colitis or Crohn's Disease in South Korea
Phase N/A · 1 location(s) · Takeda · NCT05428345
Prophylactic Dexamethasone Before Infliximab in Moderate-to-Severe IBD
Phase N/A · 1 location(s) · Second Affiliated Hospital, School of Medicine, Zhejiang Uni · NCT07385131
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintena
Phase 1/Phase 2 · 1 location(s) · National Institute of Allergy and Infectious Diseases (NIAID · NCT03167437
A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis
Phase 2 · 67 location(s) · Sanofi · NCT06975722
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Acti
Phase 3 · 46 location(s) · Sanofi · NCT07185009
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Phase 2 · 45 location(s) · Pfizer · NCT05287126
The Purpose of This Study is to Evaluate the Efficacy and Safety of 627 in the Treatment of UC
Phase 2 · 1 location(s) · Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. · NCT07507513
Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Coliti
Phase 2 · 32 location(s) · Odyssey Therapeutics · NCT06850727
A Study of MB-001 in Moderately to Severely Active Ulcerative Colitis
Phase 1/Phase 2 · 1 location(s) · Mage Biologics · NCT07374471
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Phase 3 · 47 location(s) · Alfasigma S.p.A. · NCT06865417
Clinical Trial of TQH3906 Capsules for the Treatment of Adult Patients With Moderately to Severely Active Ulcerative Col
Phase 1 · 30 location(s) · Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharm · NCT06754891
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
Phase 2 · 207 location(s) · Eli Lilly and Company · NCT06598943
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants
Phase 3 · 200 location(s) · Hoffmann-La Roche · NCT06588855
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Phase 2 · 147 location(s) · Eli Lilly and Company · NCT07186101
Real-World Effectiveness and Safety of Upadacitinib Plus Vedolizumab vs Upadacitinib Monotherapy During Induction in Mod
Phase N/A · 6 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT07442045
Study to Assess Change in Disease Activity of Risankizumab Treatment in Japanese Participants With Moderate to Severe Ul
Phase N/A · 28 location(s) · AbbVie · NCT07136116
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Phase 4 · 49 location(s) · Takeda · NCT06095128
A Phase 2 Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of HRS-7085 Tablets in Patients With Inf
Phase 2 · 1 location(s) · Shandong Suncadia Medicine Co., Ltd. · NCT07229950
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Phase 3 · 63 location(s) · Janssen Research & Development, LLC · NCT07577856
Efficacy and Safety of Vedolizumab Combined With Upadacitinib in Patients With Ulcerative Colitis
NA · 1 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT06095596
An Observational Study to Evaluate Effectiveness and Safety of Upadacitinib in Chinese Adult Participants With Moderate
Phase N/A · 3 location(s) · AbbVie · NCT06838845
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcera
Phase 3 · 189 location(s) · Eli Lilly and Company · NCT06937086
An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis
Phase N/A · 28 location(s) · Pfizer · NCT06398626
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to S
Phase 3 · 15 location(s) · Hoffmann-La Roche · NCT07158242
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Col
Phase 3 · 400 location(s) · Janssen Research & Development, LLC · NCT07196748
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn'
Phase 3 · 68 location(s) · Eli Lilly and Company · NCT04844606
A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
Phase 2 · 25 location(s) · Pfizer · NCT07470879
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Phase 2 · 258 location(s) · Eli Lilly and Company · NCT07415044
A Real-World Study of Guselkumab in Chinese Participants With Ulcerative Colitis
Phase N/A · 10 location(s) · Xian-Janssen Pharmaceutical Ltd. · NCT07302360
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