● Recruiting

A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis

Condition: Moderately to Severely Active Ulcerative Colitis · Sponsor: Hoffmann-La Roche

PhasePhase 3

Planned participants100

Who can joinAll sexes, 2 Years to 17 Years

Healthy volunteersNo

About this study

This Phase III, randomized, double-blind, multicenter, induction and maintenance study will evaluate the safety and efficacy of Afimkibart (RO7790121) in pediatric participants with moderate to severe active ulcerative colitis (UC).

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: CA45905 https://forpatients.roche.com/ No attachments to email below. · 888-662-6728 (U.S. and Canada) · global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (15)

University of South Florida	Tampa, Florida, United States	Recruiting
Children's Healthcare of Atlanta	Atlanta, Georgia, United States	Recruiting
NYU Langone Health	New York, New York, United States	Recruiting
Mater Hospital Brisbane	South Brisbane, Queensland, Australia	Recruiting
Royal Children's Hospital	Parkville, Victoria, Australia	Recruiting
Perth Children's Hospital	Nedlands, Western Australia, Australia	Recruiting
Children's Hospital ZheJiang University School of Medicine	Hangzhou, Zhejiang, China	Recruiting
Emmed Research	Pretoria, South Africa	Recruiting
National Taiwan University Hospital	Taipei, Taiwan	Recruiting
Chulalongkorn University	Bangkok, Thailand	Recruiting
Siriraj Hospital	Bangkok, Thailand	Recruiting
Ramathibodi Hospital	Bangkok, Thailand	Recruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07158242