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Condition: Brca1 Mutation Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Brca1 Mutation

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
Phase 2 · 18 location(s) · VA Office of Research and Development · NCT04038502Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations
Phase N/A · 1 location(s) · Institute of Cancer Research, United Kingdom · NCT02705846A Bidirectional Cohort Study on Prophylactic Resection Surgery in Populations at Moderate-to-High Risk for Hereditary Ov
Phase N/A · 1 location(s) · Peking University Third Hospital · NCT07532434Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer
Phase 2 · 3 location(s) · Okayama University · NCT05485766BRCA Mutation Carriers' Platform a Multicenter Study
Phase N/A · 40 location(s) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT07253051Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries
Phase N/A · 1 location(s) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT05769517Cognitive Behavioral Therapy for Fear of Cancer Recurrence in Women With BRCA1/2 Gene
NA · 1 location(s) · CHU de Quebec-Universite Laval · NCT06817694Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Phase N/A · 1 location(s) · University Health Network, Toronto · NCT03702309Study of How People Make Decisions About Prostate Cancer Risk
Phase N/A · 1 location(s) · Memorial Sloan Kettering Cancer Center · NCT07197723An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Inte
NA · 8 location(s) · Memorial Sloan Kettering Cancer Center · NCT05420064Development and Validation of an Ovarian Cancer Risk Prediction Model for Family Members of Ovarian Cancer Probands
Phase N/A · 1 location(s) · Peking University Third Hospital · NCT07039552Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors
Phase 1 · 1 location(s) · Varun Monga, MBBS · NCT06177171TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
NA · 66 location(s) · University Medical Center Nijmegen · NCT04294927MEASUREMENT OF CIRCULATING MUTATION BURDEN
Phase N/A · 1 location(s) · Centre Francois Baclesse · NCT06792721Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomark
NA · 25 location(s) · Institut Claudius Regaud · NCT05378204SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
Phase 1 · 2 location(s) · General Oncology, Inc. · NCT04150042Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Phase 1 · 18 location(s) · Duke Street Bio Ltd · NCT06458712Pancreas Registry and High Risk Registry
Phase N/A · 2 location(s) · Icahn School of Medicine at Mount Sinai · NCT02775461Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and M
Phase N/A · 1 location(s) · National Cancer Institute (NCI) · NCT04431024PARPi or Capecitabine Combined With PD-1 Inhibitors as Adjuvant Therapy in High-risk TNBC
Phase 3 · 1 location(s) · Guangdong Provincial People's Hospital · NCT06533384Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Phase 3 · 676 location(s) · NRG Oncology · NCT06580314Combination Therapy in Cancers With Mutations in DNA Repair Genes
Phase 1 · 1 location(s) · University of California, San Francisco · NCT05694715A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Phase 1/Phase 2 · 14 location(s) · 858 Therapeutics, Inc. · NCT06395519Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk
Phase N/A · 1 location(s) · Abramson Cancer Center at Penn Medicine · NCT02478892A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
NA · 549 location(s) · NRG Oncology · NCT04251052Responses to Genetic Risk Modifier Testing Among Women With Pathogenic Variants in Breast Cancer Predisposition Genes
Phase N/A · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT03396341Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
Phase 1 · 8 location(s) · Senhwa Biosciences, Inc. · NCT04890613Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breas
Phase N/A · 8 location(s) · Memorial Sloan Kettering Cancer Center · NCT00823654Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer
Phase 2 · 1 location(s) · M.D. Anderson Cancer Center · NCT04090567A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study)
NA · 1 location(s) · Vasileios Kalles · NCT07292246
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.