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Study identifier: NCT04150042 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

Condition: Pancreatic Adenocarcinoma Metastatic · BRCA1 Mutation · BRCA2 Mutation  ·  Sponsor: General Oncology, Inc.

PhasePhase 1
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The clinical trial is a phase 1, single-arm trial that will evaluate the safety of the investigational treatment on metastatic pancreatic cancer and metastatic breast cancer. The investigational treatment will involve 2 cycles of a combination of intravenous melphalan, BCNU, vitamin B12b, and vitamin C with autologous hematopoietic stem cell infusion. A dose-escalation schedule is being employed for the vitamin C.

This description comes directly from the study's public registry record.

Talk to the study team

General Oncology (study sponsor)  ·  818-4-SHARON (818-474-2766)  ·  contact@SharonTrial.com

Always discuss trial participation with your own doctor first.

Locations (2)

Massachusetts General HospitalBoston, Massachusetts, United StatesCompleted
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04150042