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Study identifier: NCT04294927 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Condition: BRCA1 Gene Mutation · BRCA2 Gene Mutation · RAD51C Gene Mutation  ·  Sponsor: University Medical Center Nijmegen

PhaseNA
Planned participants3000
Who can joinFemale, 25 Years to 50 Years
Healthy volunteersNo

About this study

The aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.

This description comes directly from the study's public registry record.

Talk to the study team

Joanne A. de Hullu, MD, PhD  ·  +31 (0) 24 36 16683  ·  Joanne.deHullu@radboudumc.nl

Karen H. Lu, MD, PhD  ·  (713) 745-8902  ·  khlu@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (66)

UChicago MedicineChicago, Illinois, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Washington University Medical CenterSt Louis, Missouri, United StatesRecruiting
Mount Sinai HospitalNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Duke University HospitalDurham, North Carolina, United StatesRecruiting
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Harris Health Lyndon B. Johnson HospitalHouston, Texas, United StatesRecruiting
MD Anderson Cancer CentreHouston, Texas, United StatesRecruiting
University of WashingtonSeattle, Washington, United StatesRecruiting
Chris O'Brien LifehouseSydney, New South Wales, AustraliaRecruiting

+ 54 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04294927