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Study identifier: NCT00823654 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

Condition: Breast Cancer  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhaseN/A
Planned participants609
Who can joinFemale, 18 Years to 44 Years
Healthy volunteersYes

About this study

The purpose of this study is to learn more about the effects of your BRCA mutation on the ovaries. The BRCA gene can make it hard to conceive a child in the future. It may also bring on early menopause. The researchers will check blood levels of hormones that the ovaries produce. The hormones that researchers will check are anti-Mullerian hormone (AMH), estradiol and follicle stimulating hormone (FSH). The researchers will do this before, during, and after cancer treatment. The researchers will also ask you to fill out questionnaires about your menstrual cycle (your periods) and information about your health and pregnancies. This may help us learn which women will be more likely to have early menopause.

This description comes directly from the study's public registry record.

Talk to the study team

Shari Goldfarb, MD  ·  646-888-5080

Minna Lee, MD  ·  646-888-6898

Always discuss trial participation with your own doctor first.

Locations (8)

Memorial Sloan Kettering Basking RidgeBasking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering MonmouthMiddletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering BergenMontvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering CommackCommack, New York, United StatesRecruiting
Memorial Sloan Kettering WestchesterHarrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
New York Presbyterian Hospital-Weill Medical College of Cornell UniversityNew York, New York, United StatesActive Not Recruiting
Memorial Sloan Kettering NassauUniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT00823654