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Condition: Advanced Intrahepatic Cholangiocarcinoma Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Advanced Intrahepatic Cholangiocarcinoma

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and
Phase 2 · 1 location(s) · Nanfang Hospital, Southern Medical University · NCT06298968Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced
Phase 2 · 1 location(s) · West China Hospital · NCT06859684Liver Transplantation in Intrahepatic Cholangiocarcinoma
Phase N/A · 2 location(s) · Rutgers, The State University of New Jersey · NCT06140134Cryoablation Combined With Lenvatinib Plus Tislelizumab Compared With FOLFOX in Patients With Advanced Intrahepatic Chol
Phase 2 · 1 location(s) · Fudan University · NCT06860477Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study
Phase 3 · 1 location(s) · Shanghai Junshi Bioscience Co., Ltd. · NCT05342194Lenvatinib Plus Sintilimab in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Liver Cancer
Phase 2 · 1 location(s) · Fudan University · NCT05010681Safety and Efficacy of CD160-Enhanced Autologous Antigen-Specific T-Cells (BTC-Ag-T) in Advanced Biliary Tract Cancer
Phase 1 · 1 location(s) · Shanghai Zhongshan Hospital · NCT07614061Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanced and Unr
Phase 2 · 1 location(s) · Tianjin Medical University Cancer Institute and Hospital · NCT06852287Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic Chol
Phase 2 · 1 location(s) · Fudan University · NCT07070700Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations
Phase 1 · 4 location(s) · Tyra Biosciences, Inc · NCT06160752Clinical Study of VG161 in Advanced Intrahepatic Cholangiocarcinoma
Phase 2 · 1 location(s) · CNBG-Virogin Biotech (Shanghai) Ltd. · NCT06746480Chidamide Combined With Chemotherapy and Immunotherapy as First-line Treatment for Advanced Intrahepatic Cholangiocarcin
Phase 2 · 1 location(s) · Shanghai Zhongshan Hospital · NCT07570849Chemotherapy Combined with Immunotherapy and Targeted Therapy in Cholangiocarcinoma
Phase N/A · 1 location(s) · Second Affiliated Hospital, School of Medicine, Zhejiang Uni · NCT06718257A Multicenter, Prospective, Randomized, Open-label Phase Ib/II Study of Celecoxib Plus Pembrolizumab and Gemcitabine/Cis
Phase 1/Phase 2 · 1 location(s) · Shanghai 6th People's Hospital · NCT07632235Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-posi
Phase 3 · 185 location(s) · Jazz Pharmaceuticals · NCT06282575HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma
Phase 2/Phase 3 · 1 location(s) · Hutchmed · NCT04353375A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α srRNA in Treating Advanced ICC Patients
EARLY_Phase 1 · 1 location(s) · Shanghai Changzheng Hospital · NCT06583993Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer
Phase 1/Phase 2 · 1 location(s) · Beijing Biotech · NCT07641036Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Ch
Phase 1 · 1 location(s) · Mayo Clinic · NCT06058663HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Adv
Phase 2 · 1 location(s) · M.D. Anderson Cancer Center · NCT06858735A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Phase 1/Phase 2 · 41 location(s) · Alentis Therapeutics AG · NCT07169734TACE Combined With Tislelizumab in Patients With Advanced Intrahepatic Cholangiocarcinoma
Phase 2 · 1 location(s) · Fudan University · NCT04954781Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio
Phase 2 · 1 location(s) · Beth Israel Deaconess Medical Center · NCT05655949Cryoablation Combined with Anti-PD-1 Antibody in Patients with Advanced Intrahepatic Cholangiocarcinoma
Phase 2 · 1 location(s) · Fudan University · NCT04299581The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments
Phase 2 · 1 location(s) · Inova Health Care Services · NCT05422690Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma After SIRT and Chemotherapy
NA · 1 location(s) · Assistance Publique - Hôpitaux de Paris · NCT06910722A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients
Phase 2 · 2 location(s) · Mehmet Akce · NCT06728410Personalized Tumor Neoantigen mRNA Therapy for Advanced Intrahepatic Cholangiocarcinoma
Phase 1/Phase 2 · 1 location(s) · Zhejiang University · NCT06956716A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Ph
Phase 3 · 18 location(s) · J-Pharma Co., Ltd. · NCT07265674
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.