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Condition: Nicotine Use Disorder Synced from ClinicalTrials.gov · July 29, 2026

Recruiting studies: Nicotine Use Disorder

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Cardiovascular Effects of Very Low Nicotine Content Cigarettes
EARLY_Phase 1 · 1 location(s) · Wake Forest University Health Sciences · NCT05707871Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
NA · 1 location(s) · National Institute on Drug Abuse (NIDA) · NCT01036581tDCS Plus Varenicline for Smoking Cessation
Phase 4 · 1 location(s) · Centre for Addiction and Mental Health · NCT06798324Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP
Phase N/A · 1 location(s) · National Institute on Drug Abuse (NIDA) · NCT06552741BREATHE Free: a Pilot Feasibility Trial
NA · 1 location(s) · Augusta University · NCT06862050The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction
Phase 2 · 1 location(s) · VapeAway · NCT07322432Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
NA · 1 location(s) · Medical University of South Carolina · NCT06678789Smoking Cessation Behavioral Treatment Study
NA · 2 location(s) · University of Missouri-Columbia · NCT03948893Re-Connect Application for Smoking Cessation
NA · 1 location(s) · Rowan University · NCT05224154Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Phase 3 · 1 location(s) · Jasper A. Smits · NCT06053567Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
EARLY_Phase 1 · 1 location(s) · Duke University · NCT05665465Effects of Cannabidiol on Stress and Nicotine Withdrawal
Phase 1 · 1 location(s) · Johns Hopkins University · NCT07001930Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault
NA · 1 location(s) · University of Washington · NCT06444295Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users
NA · 1 location(s) · University of Georgia · NCT05447325Smart Olfaction App to Reduce Relapse
EARLY_Phase 1 · 1 location(s) · University of Houston · NCT07007195TUBSIS 2.0 - Tobacco Use Behavioral Support and Intervention System
NA · 1 location(s) · University of Zurich · NCT07568483A First in Human Single Ascending Dose (SAD) Study of ATI-1013 in Healthy Smokers
Phase 1 · 1 location(s) · Antidote Therapeutics, Inc · NCT07215923Behavioral Intervention for Youth to Promote Vaping Cessation
NA · 1 location(s) · Massachusetts General Hospital · NCT06765291Effects of Switching From Cigarettes to Tobacco Heating System on Coronary Atherosclerosis Progression
NA · 1 location(s) · National Institute of Cardiology, Warsaw, Poland · NCT05660798Use of Nicotine Pouches Among Daily Smokers
NA · 2 location(s) · Milton S. Hershey Medical Center · NCT06043362Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder
Phase N/A · 1 location(s) · Prisma Health-Upstate · NCT07594717Young Adult Tobacco/Nicotine and Cannabis Co-use
NA · 1 location(s) · Medical University of South Carolina · NCT06239350Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Phase 2 · 1 location(s) · Washington State University · NCT05181891Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites
NA · 1 location(s) · University of Chicago · NCT06837220The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments
NA · 4 location(s) · Ottawa Heart Institute Research Corporation · NCT04163081Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
Phase 2 · 1 location(s) · University of California, San Francisco · NCT05999383Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community
NA · 3 location(s) · Sigmund Freud PrivatUniversitat · NCT06803706A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users
NA · 1 location(s) · Fred Hutchinson Cancer Center · NCT06909500Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
Phase 2 · 2 location(s) · University of Vermont · NCT06614504INSPIRE Respiratory Health Program in Botucatu, São Paulo, Brazil
Phase N/A · 1 location(s) · UPECLIN HC FM Botucatu Unesp · NCT06673225
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.