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Study identifier: NCT06678789 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

Condition: Cigarette Smoking · Nicotine Dependence · Smoking Cessation  ·  Sponsor: Medical University of South Carolina

PhaseNA
Planned participants50
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersYes

About this study

Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free. The present study is evaluating how well nicotine pouches, at different nicotine levels, help people switch away from smoking cigarettes. People who smoke cigarettes will be asked to answer questions about their tobacco product use and provide breath samples and cheek swab samples at an in-person visit to MUSC Charleston. Participants will then be provided with a 28-day supply of nicotine pouches, and will be asked to switch from smoking to pouches over the course of 4 weeks. Finally, participants will complete a final visit at MUSC, and will answer more questions about their tobacco use 1-month later.

This description comes directly from the study's public registry record.

Talk to the study team

Talia Ogretman  ·  843-259-8111  ·  ogretmet@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06678789