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Study identifier: NCT07001930 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of Cannabidiol on Stress and Nicotine Withdrawal

Condition: CBD · Stress · Nicotine Dependence  ·  Sponsor: Johns Hopkins University

PhasePhase 1
Planned participants90
Who can joinAll sexes, 21 Years to 70 Years
Healthy volunteersNo

About this study

The purpose of this study is to examine the effect of doses of cannabidiol (CBD) during exposure to stress and nicotine withdrawal in nicotine users. The main objectives of the study include examining the effect CBD has on stress, tobacco dependence, tobacco withdrawal, and sex differences between these types of stress. Participants will be administered CBD and exposed to stress. Biological and subjective measures will be collected. Participants may be asked to stop use for 24 hours. Researchers will also investigate withdrawal effects between participants who have not smoked nicotine in 24 hours and those who have continued to smoke before each session.

This description comes directly from the study's public registry record.

Talk to the study team

Lauren Brogdon, MHS  ·  410-550-6953  ·  lmorri20@jhmi.edu

Dustin C. Lee, PhD  ·  410-550-4035  ·  dlee@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Behavioral Pharmacology Research UnitBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07001930