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Condition: High Risk Localized Prostate Cancer Synced from ClinicalTrials.gov · July 29, 2026

Recruiting studies: High Risk Localized Prostate Cancer

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

A Randomised Trial of Cabazitaxel, Docetaxel, Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patien
Phase 2/Phase 3 · 2 location(s) · Shanghai Jiao Tong University School of Medicine · NCT03258320High Intensity Focused Ultrasound in Prostate Cancer
Phase 2 · 1 location(s) · University of Florida · NCT06402357Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer
Phase 1/Phase 2 · 1 location(s) · The Methodist Hospital Research Institute · NCT07182279ABlative Radiotherapy (for) Unfavorable Prostate Tumors 2.0
Phase N/A · 1 location(s) · University of Milano Bicocca · NCT07407608Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Pati
Phase 2 · 1 location(s) · Samsung Medical Center · NCT06461793Efficacy and Safety of Radical Prostatectomy (RP) With or Without Salvage Radiotherapy Versus RP With Extended Pelvic Ly
NA · 1 location(s) · Ruijin Hospital · NCT07115992Androgen-responsive POSLUMA-guided Intra-prostatic Boost
Phase 2 · 4 location(s) · Martin T. King, MD, PhD · NCT0739386724 Gy in One Fraction Urethral-sparing "HDR Like" SBRT for Prostate Cancer
NA · 1 location(s) · IRCCS San Raffaele · NCT05936736Study on Triple Therapy Combined With HIFU for High-Tumor-Burden mHSPC
NA · 1 location(s) · Qilu Hospital of Shandong University · NCT07172685ABlative Radiotherapy (for) Unfavorable Prostate Tumors
Phase N/A · 1 location(s) · University of Milano Bicocca · NCT04831983HIFU for Focal Ablation of Prostate Tissue: An Observational Study
Phase N/A · 1 location(s) · University of California, Los Angeles · NCT03620786Clinical Study of HIFU for Localized Prostate Cancer
Phase N/A · 1 location(s) · RenJi Hospital · NCT06362577Multi-omic Approach to Study HDR Brachytherapy for Favorable Risk and Low Tier Intermediate Risk Prostate Cancer
Phase N/A · 1 location(s) · British Columbia Cancer Agency · NCT06200974High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma
NA · 1 location(s) · Jonsson Comprehensive Cancer Center · NCT04945642Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer
Phase 2 · 1 location(s) · Mark Garzotto, MD · NCT03753243Towards Optimal Treatment for High Risk Prostate Cancer
NA · 1 location(s) · Haaglanden Medical Centre · NCT06204341Artificial Intelligence to Personalize Prostate Cancer Treatment (the HypoElect Trial)
Phase 2 · 1 location(s) · German Oncology Center, Cyprus · NCT06582446Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal)
Phase N/A · 1 location(s) · Singapore General Hospital · NCT06491056A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-r
Phase 2 · 2 location(s) · University of Chicago · NCT05726292Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer
Phase 2 · 1 location(s) · University of California, San Diego · NCT06990542Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
Phase 2 · 9 location(s) · University of British Columbia · NCT04812366Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer
NA · 1 location(s) · University of California, Davis · NCT06178354PRISM Study: Prostate Recurrence Detection Using Imaging With PSMA PET/MRI Post-high Intensity Focused Ultrasound
Phase N/A · 1 location(s) · NYU Langone Health · NCT07184970Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Pr
Phase 2 · 1 location(s) · Jonsson Comprehensive Cancer Center · NCT06067269Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA P
Phase 2 · 1 location(s) · Baptist Health South Florida · NCT07455903Focal Therapy for Localized Prostate Cancer
Phase N/A · 1 location(s) · University of California, San Diego · NCT06270043Study Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated Radiotherapy in Patients With L
Phase 3 · 6 location(s) · UNICANCER · NCT06625970Two-fraction HDR Monotherapy for Localized Prostate Cancer
NA · 1 location(s) · University of California, San Francisco · NCT05665738A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Befo
Phase 2 · 23 location(s) · Bayer · NCT07450599Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy
Phase 2 · 3 location(s) · Hackensack Meridian Health · NCT06798558
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.