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Study identifier: NCT05665738 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Two-fraction HDR Monotherapy for Localized Prostate Cancer

Condition: Prostate Adenocarcinoma · Localized Prostate Carcinoma  ·  Sponsor: University of California, San Francisco

PhaseNA
Planned participants17
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a single center single arm prospective pilot study investigating the safety of high dose rate (HDR) brachytherapy as monotherapy delivered in 2 fractions 3 hours apart. HDR monotherapy has been established as safe and effective in this context, however previous studies have delivered 2 fractions on separate days, or at least 6 hours apart. Clinically, this regimen, if shown to be safe and effective in future studies, has the potential to reduce operative resources and logistical stresses on brachytherapy departments.

This description comes directly from the study's public registry record.

Talk to the study team

Imani Dunn  ·  877-827-3222  ·  Imani.Dunn@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05665738