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Study identifier: NCT06798558 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy

Condition: Prostate Adenocarcinoma  ·  Sponsor: Hackensack Meridian Health

PhasePhase 2
Planned participants54
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Male adults with a confirmed diagnosis of prostate adenocarcinoma who meet criteria for localized high risk prostate cancer according to the NCCN guidelines and who are eligible for prostatectomy will be invited to participate. Criteria for high-risk prostate cancer include patients with preoperative prostate biopsy score of Gleason 8 (GS8) (Grade group 4 \[GG4\]) or higher. Patients also need to have a positive PSMA scan on 68-Ga-PSMA-11 PET/CT scan.

This description comes directly from the study's public registry record.

Talk to the study team

Oncology Clinical Research Referral Office  ·  551-996-1777  ·  OncologyResearchReferral@hmhn.org

Always discuss trial participation with your own doctor first.

Locations (3)

MedStar Washington Hospital CenterWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Lombardi Comprehensive Cancer Center at Georgetown University Medical CenterWashington D.C., District of Columbia, United StatesNot Yet Recruiting
John Theurer Cancer Center at Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06798558