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Study identifier: NCT05726292 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer

Condition: Prostate Cancer · Prostate Adenocarcinoma  ·  Sponsor: University of Chicago

PhasePhase 2
Planned participants90
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers conducting this study hope to learn about the safety and effectiveness of combining two study drugs, relacorilant and enzalutamide, plus androgen deprivation therapy (ADT), also known as hormone therapy. This study is for individuals who have been diagnosed with advanced, high-risk prostate cancer and standard therapies available to treat your disease have not been effective. Participation in this research will last about 3 years and 9 months.

This description comes directly from the study's public registry record.

Talk to the study team

Cancer Trials  ·  1-855-702-8222  ·  cancerclinicaltrials@bsd.uchicago.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Chicago Comprehensive Cancer CenterChicago, Illinois, United StatesRecruiting
University of Texas Southwestern Medical CenterDallas, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05726292