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Condition: Depression Unipolar Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Depression Unipolar

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
Phase N/A · 1 location(s) · The University of Hong Kong · NCT07604753Neural Response to Inflammatory Challenge in Major Depressive Disorder
Phase 1/Phase 2 · 1 location(s) · Laureate Institute for Brain Research, Inc. · NCT04751331Brief Trial of ACT-i for Adults With Chronic Insomnia
NA · 1 location(s) · Babes-Bolyai University · NCT07048600A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressi
Phase 3 · 60 location(s) · Neurocrine Biosciences · NCT07196501Intravenous Ketamine for Treatment-Resistant Depression
Phase 2 · 1 location(s) · Mayo Clinic · NCT06668571Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolesce
NA · 2 location(s) · University of Alabama at Birmingham · NCT05437588Amygdala Neurofeedback for Depression - Large Scale Clinical Trial
NA · 1 location(s) · Kymberly Young · NCT05703256Nebulized Ketamine for the Treatment of Major Depressive Disorder
Phase 3 · 1 location(s) · Theresa Jacob, PhD, MPH · NCT06752759Psychiatric Multi-omics and Neuroimaging Project
Phase N/A · 1 location(s) · mingjun Zhong · NCT06580860Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements
Phase N/A · 2 location(s) · Kernel · NCT07294924Effect of Psychobiotics With Standard Antiddepressants in Treatment of Major Depressive Disorder
NA · 1 location(s) · Dr Sadia yasir · NCT07691749Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
EARLY_Phase 1 · 1 location(s) · University of Pennsylvania · NCT06788249Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major De
Phase 3 · 3 location(s) · Khyber Medical University Peshawar · NCT07703722Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulat
Phase 4 · 2 location(s) · Region Örebro County · NCT07026461Regulation of Affect and Physiology in Depression
Phase 2 · 1 location(s) · University of Southern California · NCT06345859Reward Processing and Depressive Subtypes: Identifying Neural Biotypes
Phase N/A · 1 location(s) · San Francisco Veterans Affairs Medical Center · NCT0608064640 Hz Light Neurostimulation for Patients With Depression (FELIX)
NA · 1 location(s) · Klaus Martiny · NCT05680220Comparing Uni- and Bi-lateral TBS in Major Depression
NA · 1 location(s) · The Royal Ottawa Mental Health Centre · NCT04142996tDCS: Sleep to Mood in Depression (S2M-D)
NA · 1 location(s) · NYU Langone Health · NCT07572526A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Phase 4 · 40 location(s) · Axsome Therapeutics, Inc. · NCT06223880In Vivo Cortical Excitability Modulation in Major Depressive Disorder
Phase N/A · 1 location(s) · Fundacao Champalimaud · NCT05441969Neuromodulation and Attention Deficits in MDD
NA · 1 location(s) · University of Electronic Science and Technology of China · NCT07111169Peer-Delivered Behavioral Activation in a CCBHC
NA · 1 location(s) · Wayne State University · NCT07219394The Effects of Exercise on Gut Bacteria, Mood and Cognition in Depression
NA · 1 location(s) · University College Cork · NCT06398496Maintenance rTMS for Depression (Maitr-De)
NA · 3 location(s) · University of California, San Diego · NCT06938841RIVER At Home Ketamine Protocols
Phase N/A · 2 location(s) · RIVER Foundation · NCT06070766Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Phase 2 · 2 location(s) · Brigham and Women's Hospital · NCT06376734Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway
NA · 1 location(s) · First Affiliated Hospital of Zhejiang University · NCT05913960Group Therapy for Major Depression: Comparing Expectation-Focused and Reward-Focused Psychotherapy Approaches
NA · 1 location(s) · Philipps University Marburg · NCT07388004Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder
Phase 2 · 1 location(s) · Roger McIntyre · NCT07523048
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.