● Recruiting

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

Condition: Major Depressive Disorder · Sponsor: Axsome Therapeutics, Inc.

PhasePhase 4

Planned participants350

Who can joinAll sexes, 18 Years to 65 Years

Healthy volunteersNo

About this study

This is a randomized, double-blind, active-controlled, multi-center study to evaluate the efficacy of AXS-05, compared to bupropion, in preventing the relapse of depressive symptoms in subjects with major depressive disorder (MDD) who have responded to treatment with AXS-05.

This description comes directly from the study's public registry record.

Talk to the study team

Study Director · +1 (212) 332-5061 · axs-05-mdd-401@axsome.com

Always discuss trial participation with your own doctor first.

Locations (40)

Clinical Research Site	Bellflower, California, United States	Recruiting
Clinical Research Site	Lafayette, California, United States	Recruiting
Clinical Research Site	Oceanside, California, United States	Recruiting
Clinical Research Site	Redlands, California, United States	Recruiting
Clinical Research Site	Riverside, California, United States	Recruiting
Clinical Research Site	San Diego, California, United States	Recruiting
Clinical Research Site	Upland, California, United States	Recruiting
Clinical Research Site	Brandon, Florida, United States	Recruiting
Clinical Research Site	Doral, Florida, United States	Recruiting
Clinical Research Site	Hialeah, Florida, United States	Recruiting
Clinical Research Site	Jacksonville, Florida, United States	Recruiting
Clinical Research Site	Miami, Florida, United States	Recruiting

+ 28 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06223880