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Study identifier: NCT04090411 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

Condition: Moderate to Severe Ulcerative Colitis  ·  Sponsor: Hoffmann-La Roche

PhasePhase 2
Planned participants246
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This phase 2b study is designed to have all subjects go into a 12 week induction period to compare different doses of study drug against placebo. After induction is complete all subjects will receive active therapy for 40 weeks, followed by a 12 week follow up period.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (166)

Digestive Health SpecialistsDothan, Alabama, United States
Dothan Surgery CenterDothan, Alabama, United States
Flowers HospitalDothan, Alabama, United States
Lynn Institute of the OzarksLittle Rock, Arkansas, United States
Surinder Saini, M.D., Inc.Newport Beach, California, United States
Endoscopy Center of Connecticut, LLCGuilford, Connecticut, United States
Endoscopy Center of Connecticut, LLCHamden, Connecticut, United States
Medical Research Center Of Connecticut, LLCHamden, Connecticut, United States
PACT Gastroenterology CenterHamden, Connecticut, United States
Whitney ImagingHamden, Connecticut, United States
Medycal Research Inc.Brooksville, Florida, United States
Safety Harbor SurgeryClearwater, Florida, United States

+ 154 more locations — full list on the registry record.

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