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Condition: Severe Immune Deficiency Synced from ClinicalTrials.gov · July 29, 2026

Recruiting studies: Severe Immune Deficiency

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Study of Populations at Risk of Developing Chronic Hepatitis Linked to Chronic Enteric Virus Infection in Patients With
Phase N/A · 3 location(s) · Assistance Publique - Hôpitaux de Paris · NCT06659588Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodefic
Phase 1/Phase 2 · 1 location(s) · National Institute of Allergy and Infectious Diseases (NIAID · NCT01306019Gene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)
NA · 1 location(s) · Shenzhen Geno-Immune Medical Institute · NCT03645460Genetic Basis of Immunodeficiency
Phase N/A · 1 location(s) · National Heart, Lung, and Blood Institute (NHLBI) · NCT00055172Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
Phase 1 · 7 location(s) · AIDS Malignancy Consortium · NCT05077527Autologous Gene Therapy for Artemis-Deficient SCID
Phase 1/Phase 2 · 1 location(s) · University of California, San Francisco · NCT03538899A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Pre
Phase 3 · 62 location(s) · Grifols Therapeutics LLC · NCT05645107A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patie
NA · 1 location(s) · Daniel Morgenstern · NCT06519682The Experience of Screening for SCID
Phase N/A · 1 location(s) · King's College London · NCT05651113Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifest
Phase 2 · 1 location(s) · Paul Szabolcs · NCT07284641Targeting Real World Usage In Stroke Treatment
Phase N/A · 13 location(s) · Phenox GmbH · NCT07474935Systematic Screening for Primary Immunodeficiencies in Patients Admitted for Severe Infection in Pediatric Intensive Car
Phase N/A · 1 location(s) · University Hospital, Montpellier · NCT04990908Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of
Phase N/A · 1 location(s) · Syneos Health · NCT00404989Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning
Phase 1/Phase 2 · 4 location(s) · David Williams · NCT03311503Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Phase N/A · 2 location(s) · Sanford Health · NCT01793168Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies
Phase N/A · 1 location(s) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT06941584Risk Identification Factors for Pulmonary Function Impairment in AIDS Patients Recovered From Severe Pneumonia
Phase N/A · 1 location(s) · Guangzhou 8th People's Hospital · NCT06137196Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC
Phase N/A · 1 location(s) · Paul Szabolcs · NCT04528355SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection
Phase 1/Phase 2 · 1 location(s) · Shenzhen Geno-Immune Medical Institute · NCT03217617Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemor
Phase N/A · 1 location(s) · M.D. Anderson Cancer Center · NCT06181656Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency
Phase 1 · 1 location(s) · Great Ormond Street Hospital for Children NHS Foundation Tru · NCT03601286Evaluation of Patients With Immune Function Abnormalities
Phase N/A · 1 location(s) · National Institute of Allergy and Infectious Diseases (NIAID · NCT00128973Clinical Application of Cytokine Adsorption Technique in AIDS Patients With Severe Pneumonia and/or Septic Shock
Phase N/A · 1 location(s) · Guangzhou 8th People's Hospital · NCT06145828Metagenomic Next-Generation Sequencing Guides Anti-Infection Strategies
Phase N/A · 1 location(s) · Guangzhou 8th People's Hospital · NCT06145841Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform
Phase N/A · 1 location(s) · Shwachman-Diamond Syndrome Alliance Inc · NCT06999954Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
Phase 2 · 1 location(s) · Paul Szabolcs · NCT01962415Supporting Weak Immune System During Autoimmune Therapy: Testing Panzyga to Prevent Infections
Phase 3 · 1 location(s) · Octapharma · NCT07220915The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunoco
Phase N/A · 1 location(s) · National Institute of Allergy and Infectious Diseases (NIAID · NCT01011712Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expr
Phase 1/Phase 2 · 1 location(s) · Assistance Publique - Hôpitaux de Paris · NCT05071222Gene Therapy for Adenosine Deaminase Severe Combined Immune Deficiency Using Peripheral Blood and EFS ADA Vector
Phase 1/Phase 2 · 1 location(s) · University of California, Los Angeles · NCT05432310
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.