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Study identifier: NCT03645460 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Gene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)

Condition: Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)  ·  Sponsor: Shenzhen Geno-Immune Medical Institute

PhaseNA
Planned participants10
Who can joinAll sexes, 1 Month to no upper limit
Healthy volunteersNo

About this study

This is a Phase I/II trial of in vivo lentiviral gene therapy for treating adenosine deaminase severe combined immunodeficiency (ADA-SCID) using a self-inactivating lentiviral vector (LV) ivlv-ADA to functionally correct the genetic defect. The primary objectives are to evaluate the safety and efficacy of the direct intravenous (iv) LV gene therapy protocol.

This description comes directly from the study's public registry record.

Talk to the study team

Lung-Ji Chang, Ph.D  ·  +86 0755-86573763  ·  c@szgimi.org

Always discuss trial participation with your own doctor first.

Locations (1)

Shenzhen Geno-immune Medical InstituteShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT03645460