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Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation and Bolus Maintenance in Adults
Condition: Neuromuscular Blockade · Sponsor: Jiangsu HengRui Medicine Co., Ltd.
About this study
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium. The primary objective is to assess the efficacy of HRS-9190 in providing adequate neuromuscular blockade for successful tracheal intubation. Secondary objectives include evaluating the onset time and duration of action following each dose, the total time adequate muscle relaxation is maintained during surgery, and the detailed pattern of neuromuscular recovery. Safety assessments will include monitoring of adverse events, vital signs, laboratory parameters, and other safety indicators throughout the study period. The hypothesis of this study is that HRS-9190 for Injection could provide effective neuromuscular relaxation, with a satisfied safety profile in the target patient population.
This description comes directly from the study's public registry record.
Talk to the study team
Lei Tang · +0518-81220121 · lei.tang.lt31@hengrui.com
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Locations (2)
| The Third Xiangya Hospital of Central South University | Changsha, Hunan, China | — |
| The First Affiliated Hospital of Wenzhou Medical University | Wenzhou, Zhejiang, China | — |
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Source record: clinicaltrials.gov/study/NCT07746726